The United States Food and Drug Administration (FDA) has granted fast track designation to United States-based Moderna for its investigational Zika vaccine, mRNA-1893, it was reported yesterday.
Presently, the mRNA-1893 vaccine is being evaluated in a phase one study to prevent Zika virus infection in healthy adults. The product included an mRNA sequence that encodes for the structural proteins of Zika virus. It is designed to help cells to secrete virus-like particles, helping to mimic the response of the cell after natural infection.
The phase 1 trial is evaluating the safety, pharmacokinetics and pharmacodynamics of the product in healthy volunteers. The company's randomised, observer-blind, placebo-controlled and dose-ranging study has been framed to evaluate the safety, tolerability and immunogenicity of mRNA-1893 in healthy flavivirus seropositive and seronegative adults aged between 18 and 49 years.
Pfizer reports positive Phase 3 data for ABRYSVO in adults at risk for RSV disease
Clover Bio announces SCB-1019 vaccine candidate Phase I trial data in initial young adult cohort
Sanofi launches Verorab for rabies prophylaxis in UK
BioVaxys expands patent portfolio for DPX delivery platform and advances DPX SurMAGE
YS Biopharma repays USD40m loan facility
Kintara Therapeutics and TuHURA Biosciences to merge
VGXI names new chief accounting officer
Moderna reports positive interim results from next-generation COVID-19 vaccine trial
Valneva launches Phase 1 trial for next-generation Zika vaccine
Circio Holding ASA confirms licensing deal with IOVaxis Therapeutics in China and Singapore
Everest Medicines names new chief medical officer and chief product officer
Pfizer's PREVENAR 20 gains European Commission approval for paediatric pneumococcal vaccine