Israeli commercial stage biopharmaceutical company BioLineRx Ltd (NASDAQ: BLRX) (TASE: BLRX) announced on Thursday that it has signed a licence agreement with Ayrmid Ltd, the UK-based parent company of Gamida Cell Ltd.
This agreement covers motixafortide (commercially sold in the United States as APHEXDA), BioLineRx's FDA-approved stem cell mobilisation agent indicated in combination with filgrastim (G-CSF) for collection and subsequent autologous transplantation in patients with multiple myeloma.
Under the terms of the agreement, BioLineRx grants Ayrmid an exclusive licence to develop and commercialise APHEXDA (motixafortide) across all indications, excluding solid tumour indications, and in all territories other than Asia. In exchange, BioLineRx will receive a USD10m upfront payment and is also eligible to receive up to an additional USD87m of potential commercial milestones, and royalties ranging from 18% to 23% on net sales of APHEXDA.
Ayrmid will add APHEXDA to its commercial portfolio, which also includes Gamida Cell's OMISIRGE, the first and only FDA-approved, nicotinamide (NAM)-modified cell therapy for patients with haematologic malignancies in need of a stem cell transplant.
Sanofi's efdoralprin alfa shows superior results in phase 2 study for AATD
FDA accepts Xspray Pharma's NDA for XS003 with PDUFA date set for June 2026
Citius Oncology and McKesson sign US distribution agreement for LYMPHIR
Cumberland Pharmaceuticals adds FDA-approved oral capsule for H. pylori to commercial portfolio
Genentech's Gazyva (obinutuzumab) receives US FDA approval to treat adults with lupus nephritis
AstraZeneca wins US FDA approval for Tezspire in chronic rhinosinusitis with nasal polyps
Antengene reveals ATG-022 clinical data at ESMO 2025
WeightWatchers launches RxFlexFund to expand affordable GLP-1 access for employers and employees
Sebela's MIUDELLA Hormone-Free Copper IUS recognised in TIME's best inventions of 2025
Merck reports positive Phase 3 data for investigational two-drug HIV regimen doravirine/islatravir
60 Degrees reports first patient has tested negative for babesiosis in tafenoquine study
Minovia Therapeutics' MNV-201 receives FDA Orphan Drug Designation for Myelodysplastic Syndrome