Policy & Regulation
Compass Pathways meets primary endpoint in landmark Phase 3 trial for psilocybin-based depression treatment
23 June 2025 -

Biotechnology companyCompass Pathways plc (Nasdaq: CMPS) announced on Monday that it has successfully met the primary endpoint in its Phase 3 COMP005 trial evaluating COMP360, a proprietary synthetic psilocybin, for treatment-resistant depression (TRD). A single 25 mg dose of COMP360 produced a statistically significant and clinically meaningful reduction in depression symptoms compared to placebo, with a mean difference of -3.6 on the Montgomery-Åsberg Depression Rating Scale (p

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